Clinical Data Management (CDM) operations have become a strategic priority for life sciences enterprises as they face growing trial complexities, expanding data volumes, and the integration of decentralized and real-world data sources. These dynamics are reshaping how enterprises approach data standardization, validation, and delivery, placing greater emphasis on speed, accuracy, and regulatory compliance. This report provides an in-depth assessment of leading CDM providers and their capabilities across the CDM value chain – from trial start-up to closeout. It examines how providers are leveraging AI, generative AI, and agentic AI to drive automation in data ingestion, real-time validation, medical coding, and query management. The report is particularly relevant for business and procurement leaders seeking to balance costs, compliance, and quality in an evolving CDM landscape. In this report, Everest Group comprehensively evaluates 7 leading providers featured in the CDM Operations PEAK Matrix® Compendium report. Each provider profile highlights the service focus, key IP/solutions, and domain-specific investments. By benchmarking providers across key capability dimensions, the report supports life sciences enterprises in selecting the right partners to enable next-generation data operations and accelerate clinical development outcomes.

The surge in case volumes, more stringent regulatory demands, and therapeutic areas’ rising complexities are significantly transforming pharmacovigilance (PV). As the industry adapts to more tailored reporting requirements and longer patient monitoring periods, enterprises are under pressure to optimize operations without compromising quality. This evolution has led to a reassessment of sourcing strategies, with many exploring flexible engagement models and realigning investments to balance cost and efficiency. Providers are responding by deepening their therapeutic expertise, expanding their service offerings, and integrating automation and analytics throughout the value chain. Adopting AI-enabled tools, predictive signal detection, and real-world data is accelerating operational agility and regulatory compliance. Meanwhile, commercial models are shifting away from transactional engagements toward hybrid and value-linked constructs. These shifts are intensifying competition among CROs, BPOs, and niche players, each aiming to demonstrate adaptability, innovation, and compliance strength. The report helps business and procurement leaders understand how to evolve sourcing approaches to meet future demands while ensuring long-term PV resilience.

Pharmacovigilance (PV) operations have become a strategic priority for life sciences enterprises facing heightened regulatory scrutiny, evolving safety standards, and growing complexity across global markets. This report provides an in-depth assessment of 12 leading PV service providers and their capabilities across the PV value chain, including case processing, literature surveillance, medical assessments, and regulatory reporting. The research also examines how providers are integrating automation, analytics, and platform-based solutions to drive efficiency, improve compliance, and enhance data quality. In addition, it evaluates providers’ delivery footprints, service portfolios, and investment activity, enabling enterprises to make informed sourcing decisions. The report is particularly relevant for business and procurement leaders seeking to balance cost, compliance, and quality in an evolving PV landscape. By benchmarking providers across vital dimensions, the report supports enterprises in optimizing operations and safeguarding patient safety at scale.

Clinical Data Management (CDM) is rapidly transforming as life sciences enterprises navigate increasing trial complexity, heightened regulatory scrutiny, and the expansion of decentralized and real-world data sources. CDM now plays a strategic role in enabling faster, more reliable trial outcomes through harmonized data practices. To address this shift, providers are integrating AI, generative AI, and automation throughout the CDM lifecycle, enhancing efficiency in data ingestion, validation, medical coding, and protocol design. These advances, coupled with global delivery capabilities and deep therapeutic expertise, are empowering enterprises to scale operations and navigate patient-centric trials’ demands. In response to evolving market needs, providers are also expanding their portfolios to offer comprehensive, end-to-end solutions across the CDM value chain. In this report, Everest Group comprehensively evaluates 22 leading providers featured in the Clinical Data Management Operations PEAK Matrix® report. It highlights each provider’s service focus, key IP/solutions, domain-specific investments, and case studies.

Life sciences enterprises are increasingly turning to Real-world Evidence (RWE) as an essential input for decision-making across the product life cycle – from early-stage R&D to post-market access and safety. RWE offers validated insights into treatment effectiveness, patient outcomes, and safety, but fragmented data sources, inconsistent quality, and evolving compliance expectations often challenge its generation. With the rising volume and diversity of Real-world Data (RWD), traditional analytics approaches are no longer sufficient. AI, including technologies such as NLP, machine learning, and generative models, is redefining how RWE is produced and operationalized. AI is accelerating data curation, enabling predictive analytics, and delivering regulatory-grade evidence at scale. This Viewpoint outlines how AI is transforming the RWE landscape across six domains: drug discovery, clinical trials, manufacturing, commercialization, pharmacovigilance, and regulatory affairs. It also explores emerging models such as insights-as-a-service and autonomous evidence networks, which offer scalable, modular engagement approaches for AI-powered RWE. The report provides practical recommendations for both enterprises and providers, covering capability investments, infrastructure modernization, governance models, and partnership strategies. It aims to help stakeholders reimagine their data-to-evidence journeys and build future-ready ecosystems for continuous, AI-enabled insight generation. Scope Industry: life sciences Geography: global Contents In this report, we examine: RWE’s current landscape and growing importance in life sciences AI’s role in addressing foundational RWE challenges AI-enabled key RWD/RWE use cases across the product life cycle Emerging engagement models such as BPaaS, AaaS, and IaaS Future-forward models, including autonomous evidence networks and modular AI-enabled partnerships Strategic considerations to operationalize AI-powered RWE for enterprises and providers

As life sciences enterprises navigate the clinical development’s growing complexity due to advanced therapies, increased data volumes, and the need for operational agility, outsourcing models are evolving in response. Sponsors now seek flexible, cost-efficient, and expertise-driven models to accelerate time-to-market and maintain regulatory compliance. This Viewpoint examines core characteristics, market shifts, and strategic implications of Full-service Outsourcing (FSO) and Functional Service Provider (FSP) models in clinical operations. Sponsors can benefit from tailored insights to assess and refine their clinical outsourcing strategy. The report explores the increasing adoption of hybrid models, the rising influence of AI and cloud-based infrastructures, and key decision-making factors, such as therapeutic complexity and trial geography. It highlights how enterprises can unlock greater control, scalability, and innovation in clinical trials by selecting the right outsourcing mix. It empowers decision-makers with strategic insights to navigate evolving outsourcing models, enabling them to enhance operational agility, optimize costs, and maintain greater oversight. Scope Industry: life sciences Geography: global Contents In this report, we examine FSO and FSP outsourcing models’ features and use cases Market trends influencing the shift in outsourcing approaches Key decision-making factors for selecting the right model Challenges in implementing and optimizing outsourcing strategies The growing relevance and advantages of hybrid models in clinical operations